This course will provide a proactive approach and insight into the prevention of the increasing problem of prescription drug abuse and misuse. It will review the pharmacy tragedies taking place on Long Island and the prescription drug abuse in the U.S.A. The Nassau County Executive’s Task Force on the Prevention of Drug Abuse and Misuse will be discussed, including the possible recommendations from the Task Force, which include aspects that will affect Dentistry. The course will review controlled substances as well as proper prescribing methodologies. The most common methods of prescription drug diversion will be analyzed such as doctor shopping, drug seeking behavior, prescription pad security, and proper prescription protocol.